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Jerzy Silberring

prof. dr hab. Jerzy Silberring

Kierownik

 

Więcej informacji

 

EDUCATION

M.Sci.-    Chemistry                           Jagiellonian University, IX.1974. Cracow, Poland

Ph.D.-     Chemistry                            Jagiellonian University, IX.1978. Cracow, Poland

Docent - Biochemistry                      University of Uppsala,    III.1991. Uppsala, Sweden,

Docent - Biochemistry                      Jagiellonian University, VI. 1997, Krakow, Poland

Professor - Biochemistry                   Jagiellonian University, I. 2001, Krakow, Poland

 

PROFESSIONAL EMPLOYMENT

  • Assistant Instructor, Department of Endocrinology, The Medical Academy of Cracow, IV.1974 - IX.1978.
  • Assistant Professor, Department of Endocrinology, The Medical Academy of Cracow, X.1978 - VI.1985.
  • Assistant Professor, Institute of Pharmacology, Polish Academy of Sciences, Cracow, 1985 - III.1987.
  • Senior Research Assistant, Department of Pharmacology, University of Uppsala, IV.1987 - IX.1990.
  • Associate Professor, Dept. Drug Dependence Research, Karolinska Inst., Stockholm, 1990 - 1996.
  • Responsible for the Biomedical Mass Spectrometry Laboratory at the Dept. Drug Dependence Research, Karolinska Institute.
  • Associate professor, Faculty of Chemistry, Jagiellonian University, Krakow, Poland. 1996 - 2001.
  • Professor (Biochemistry), Department of Chemistry, Jagiellonian University, Krakow, Poland. I.2001 - present
  • Head, Dept. Neurobiochemistry, Faculty of Chemistry, Jagiellonian University, Krakow, XII.1996-present
  • Consultant (mass spectrometry, biochemistry), Centre for the Polymer Chemistry, Polish Academy of Sciences, Zabrze. 1998 - 2001.
  • Deputy Head: Regional Laboratory for Physicochemical Analyses, Jagiellonian Univ., XII.2002 - 2005
  • Head, Department of Biochemistry and Neurobiology, AGH University of Science and Technology, Krakow, Poland. 21.XII.2009 - present

 

ACADEMIC HONORS AND AWARDS

  • Annual Award of The Polish Biochemical Society, 1975.
  • Scholar Award of The Jagiellonian University Faculty Association, 1976.
  • Presidential Award for Excellence in Research, Medical Academy of Cracow, 1980.
  • Presidential Award for Excellence in Research, Jagiellonian University, 1985.
  • Award from the A. Krzyżanowski Foundation, Jagiellonian University, 2000.
  • Consultant, Gerson Lehrman Group Healthcare Council, USA, 2005 - present
  • Award from the Minister of Health, Poland, 2009.

 

GRANT SUPPORT (selected)

  • Research Grants from Systembolaget, Stockholm, 1991 - 1992 and 1995-1996.
  • Research grant from NIH, USA, 1992-1997.
  • Research grant from the Polish State Committee for Scientific Research, 1999-2002.
  • Research grant (equipment) from the Polish State Committee for Scientific Research, 2001.
  • Research grant Elsa and Arvid K:son Foundation, Goteborg, Sweden, 2002 and The Sylvan´s Foundation, Goteborg, Sweden. Investigations on the mechanisms involving defensins in the immune system 2002. travel and accommodation funding.
  • Research grant from the Polish State Committee for Scientific Research, 2003-2006. Proteome identification of CNS in drug dependence. 3P04B 02024. principal investigator.
  • Research Grant from the Centre for Genetic Engineering and Biotechnology, Proteome of CNS in Drug Dependence Trieste, Italy, 2006-2008. principal investigator.
  • Research grant: Polymer-peptide arrays- structure-function dependence and arrays activity N N209 756 740. 2011-2013 – investigator
  • Research grant: (polymer nanocontainers for encapsulation of biologically active NN 209 144 136 2010-2012. - investigator
  • Research grant Functionalization of arrays with molecular receptors for MALDI MS. 2009-2012. 0286/B/H03/2009/36 (N N204 028636) - investigator
  • Research grant from the Ministry of Higher Education, Poland. 2009-2012. Identification of bioactive crypteins in CNS. 3048/B/H03/2009/37 (N N204 304837) principal investigator
  • Research grant EuroNanoMed (Polish-German) Metastases Targeting Aptamers – nucleic acid-guided therapy and diagnosis 2012-2016 - Coordinator of Polish work package

 

PUBLICATIONS (All publications)

Over 200 papers, mainly on proteolytic enzymes and their inhibitors, neuropeptides, pharmacology of pain and drug addiction, and mass spectrometry/proteomics.

Overall citations (since 1996): ca. 1500

Index "h" = 21

  1. Bodzon-Kułakowska A, Kułakowski K, Drabik A, Moszczynski A, Silberring J, Suder P. Morphinome--a meta-analysis applied to proteomics studies in morphine dependence. Proteomics. 2011 11(1):5-21. IF=4.426
  2. Suder P, Bodzon-Kulakowska A, Mak P, Bierczynska-Krzysik A, Daszykowski M, Walczak B, Lubec G, Kotlinska JH, Silberring J. The proteomic analysis of primary cortical astrocyte cell culture after morphine administration. J Proteome Res. (2009) 8(10):4633-40. IF=5.132; citations: 4
  3. Silberring J, Ciborowski P. Biomarker discovery and clinical proteomics. Trends Analyt Chem. 2010;29(2):128-47. IF=6.546; citations: 4
  4. Piotr Suder, Anna Bierczynska-Krzysik, Agnieszka Kraj, Peter Brostedt, Pawel Mak, Maciej Stawikowski, Krzysztof Rolka, Fred Nyberg, Erik Fries, and Jerzy Silberring (2007) Identification of bikunin as an endogenous inhibitor to dynorphin convertase in human cerebrospinal fluid. FEBS J. 273/22, 5113-20. IF=3.396; citations: 2
  5. Marek J. Noga, Jakub J. Lewandowski, Piotr Suder, Jerzy Silberring (2005) An enhanced method for peptides sequencing by N-terminal derivatization and mass spectrometry. Proteomics 5(17):4367-75. IF=5.735, citations: 14
  6. Drabik A, Bierczynska-Krzysik A, Bodzon-Kulakowska A, Suder P, Kotlinska J, Silberring J. (2007) Proteomics in neurosciences. Mass Spectrom. Rev. 26/3, 432-50. IF=10.947; citations: 18
  7. Wade D, Flock JI, Edlund C, Lofving-Arvholm I, Sallberg M, Bergman T, Silveira A, Unson C, Rollins-Smith L, Silberring J, Richardson M, Kuusela P, Lankinen H. Antibiotic properties of novel synthetic temporin A analogs and a cecropin A-temporin a hybrid peptide. Protein peptide Lett.  9/6 (2002) 533-543. IF=1.755; citations: 13
  8. Bergquist J., Sciubisz A., Kaczor A. and Silberring J. (2002) Catecholamines and methods for their identification and quantitation in biological tissues and fluids. J. Neurosci. Meth. 113, 1-13. IF=2.295; citations: 42
  9. Suder P., Kotlińska J., Sciubisz A., Legowska A., Eilmes J., Rolka K., and Silberring J. (2001) N-terminal glycine is crucial for hyperalgesic activity of nociceptin/orphanin FQ(1-6) Eur. J. Pharmacol 419, 33-37. IF=2.585; citations: 3
  10. David Wade, Jerzy Silberring, Rabah Soliymani, Sami Heikkinen, Ilkka Kilpeläinen, Hilkka Lankinen and Pentti Kuusela (2000) Antibacterial activities of temporin A analogs. FEBS Lett. 479, 6-9. IF=3.541; citations: 53

 

TEACHING EXPERIENCE

  • Graduate Student Program, Department of Endocrinology, The Medical Academy of Cracow. Lecturer at The Postgraduate Center in Warsaw. Theory and Application of Radioimmunoassays and Related Procedures. I.1975 - XII.1983.
  • Lecturer at The Interregional Training Course, organized by The International Atomic Energy Agency (Vienna). Kinetics of Hormone-Receptor Interactions. 1978.
  • Graduate Student Program, Department of Pharmacology, University of Uppsala. X.1989. - V.1991.
  • Graduate and Postgraduate Student program, Department of Drug Dependence Research, Karolinska Institute, I.1991.- 1996.
  • Graduate and postgraduate student programs, Departments of Chemistry and Biology, Jagiellonian University, Krakow, Poland. 1997- 2009.   (basics of biochemistry, neurochemistry, instrumental analysis, proteomics).
  • Coordinator: Biomedical Chemistry, 2003-2008
  • Faculty Committee for Ph.D.-studies (member). 2000 – 2009
  • Postgraduate student program, Faculty of Chemistry, University of Torun (protein chemistry, neuropharmacology, mass spectrometry, proteomics, metabolomics) 2007-2011.
  • Graduate medical student program, Collegium Medicum, Jagiellonian University (Neurobiological basis of behavior) 2010-present
  • Graduate medical student program, Collegium Medicum, Jagiellonian University (Neurobiological basis of drug dependence) 2011-present
  • Undergraduate  student program, AGH University of Science and Technology (Biochemistry, Neuropharmacology, Drug dependence) 2010 – cont.

 

PROFESSIONAL ORGANIZATION MEMBERSHIPS

  • Nuclear Medicine Committee of the Polish Academy of Sciences, 1979 - 1983.
  • European Neuropeptide Club 1990 - present.
  • European Society for Neurochemistry, 1991 - present.
  • Swedish Medical Research Council's Planning Group: Structure and function of bioactive peptides, 1995 -1996
  • Polish Society for Mass Spectrometry. 1997 – 2006 Vice-president.
  • Jagiellonian University Senate Ethical Committee. 2000 – 2002
  • Scientific Board, Centre for Polymeric and Carbon Materials, Polish Acad. Sci. Zabrze - member, 2007-present

 

MAJOR ACHIEVEMENTS

  • Co-discovery of LVV-hemorphin-7.
  • Co-discovery of beta-casomorphin-8 in human milk in postpartum psychosis.
  • Discovery and identification of a novel family of proteinases (dynorphin converting enzymes) involved in pain and drug abuse.
  • Discovery of an endogenous inhibitor of dynorphin converting enzyme from human CSF (bikunin)
  • Discovery of cryptein type 3: NPFF precursor (85-99) and its pharmacological function.
  • Discovery of cryptic sequences in CART precursor and their pharmacological functions
  • Discovery of a novel mechanism of pain control via NMDA receptors.
  • Co-discovery of catecholamines in the immune system
  • Co-editor of the "Mass Spectrometry – and Hyphenated Techniques in Neuropeptide Research -2002; Wiley & Sons, USA.
  • Co-editor of the "Mass Spectrometry for Graduate Students", Wiley & Sons, 2006/2007
  • Co-editor of "Proteomics for Graduates", Wiley & Sons, 2007
  • Co-Editor of "Proteomics", EJB, Krakow, 2004
  • Co-Editor of "Mass Spectrometry", Jagiellonian University, Krakow, 2006
  • Co-Editor of the "Peptides'2006" Proceedings of the 29th European Peptide Symposium
  • Member of the Editorial Board Open Enzyme Inhibition Journal (Bentham) 2008
  • Member of the Editorial Board Open Pain Journal (Bentham) 2008

 

LANGUAGE SKILLS

English (Cambridge FC) - good; Swedish (Rikstest) - fluent

 

HOBBY

Skiing, jogging, Aikido

 

 

 

Wywiad dla czasopisma studentów UJ